Advances in Clinical Chemistry, Vol. 6 by Harry Sobotka (Ed.), C.P. Stewart (Ed.) PDF

By Harry Sobotka (Ed.), C.P. Stewart (Ed.)

ISBN-10: 0120103060

ISBN-13: 9780120103065

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There is, as it were, an archipelago of islets of knowledge set in a sea of ignorance. As in the case of potassium, concerning the metabolism of which our knowledge only a score of years ago was equally scanty, much of our ignorance about magnesium is due to our inability to measure it accurately and conveniently; as in the case of potassium also, this difficulty is now in a fair way to be removed-and by the same means, flame spectrophotometry in one form or another. The decade which Elkinton forecast as being necessary for elucidation of the problems of magnesium metabolism is still only half gone.

Naturally, when debilitated patients are subjected to surgery and then for long periods given magnesium-free fluids parenterally, signs of magnesium deficiency are particularly likely to occur. Despite the absence of a clear demonstration that there was a causal relationship between a lowered plasma concentration of magnesium and the occurrence of tetany, the term “hypomagnesemic tetany” had crept into textbooks prior to the work of Vallee et al. , D8, M11, N3). ” Hanna et al. (H6) consider that gross magnesium deficiency may produce convulsions but that tetany is not present unless there is also hypocalcemia and this is supported by the case described by MacIntyre et al.

N. , The accuracy of the micro determination of the PCO, of blood from the ear lobe. Clin. Actu 6, 34-37 ( 1961). M3. , Electrochemical aspects of blood pH measurements. In “A symposium on pH and Blood Gas Measurement. Methods and Interpretations” ( R . F. ), pp. 19-29. Churchill, London, 1959. ACID-BASE VALUES OF BLOOD 27 M4. , The quantitative determination of surplus amounts of acid or base in the human body. Scand. J. Clin. Lab. Invest. 12, 187-199 ( 1960). M5. , The Hydrogen Ion Concentration in Arterial Blood.

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Advances in Clinical Chemistry, Vol. 6 by Harry Sobotka (Ed.), C.P. Stewart (Ed.)


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